10 Great Reasons to Upgrade to
BIOQUANT Life Science 2018

Is your lab using an earlier version of BIOQUANT? Need to justify an upgrade to the latest version? Here are 10 reasons to upgrade to the latest version of BIOQUANT Life Science.


Reason #1: Faster Digital Cameras


BIOQUANT now supports the JENOPTIK GRYPHAX® PROKYON camera from Jenoptik.

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Jenoptik equips the JENOPTIK GRYPHAX® PROKYON microscope cameras with the latest CMOS technology. Short exposure times and high image refresh rates make the system time-saving and convenient to use. This means you can position and focus fast and easily.

BIOQUANT is currently offering a 20% discount on the JENOPTIK GRYPHAX® PROKYON camera for the trade in of your existing camera.

Features include:

  • High image quality: 2.1, 9.2, or 20.7 megapixel image size. Pixel size 5.86 x 5.86 μm, 12 Bit, Dynamic range 73.3 dB, True color camera.

  • Sensitivity: Exposure up to 60 seconds and Gain up to 30.

  • Ease of use: Free JENOPTIK GRYPHAX® microscope camera software, large field of view 1/1.2“, 60 fps @ 2.3 MPix and no external power supply needed.

  • Stability: SONY Sensor – back illuminated, Made in Germany, 24 month warranty and software updates free of charge.

  • Live integration with BIOQUANT

  • USB 3.0 camera interface

  • In BIOQUANT, camera resolution in LIVE mode 1280 x 960 pixel (60 fps)

  • In BIOQUANT, camera resolution in HELD mode 1280 x 960 pixel, 2560x1920 pixel, or 3840 x 2880 pixel. All held image resolutions compatible with BIOQUANT live image calibration. Redraw tracings at any size. Zoom in to higher resolution at any point.

  • In GRPHAX software, camera resolution in HELD mode 1920x1200 pixel, 3840 x 2400 pixel, and 5760 x 3600 pixel.


Reason #2: Faster Skeletal Muscle Analysis


Automated analysis of myofibers depends on a high-contrast label applied to the boundary of each myofiber. Generally this requires a label specific to dystrophin or laminin.

Automatic color thresholding uses this boundary stain to identify the myofibers. Manual editing with a brush and eraser makes it simple to correct mistakes.

Intelligent filters remove previously measured myofibers and myofibers that are not entirely visible within the field of view.

BIOQUANT simultaneously collects the following data from each myofiber:

  • Myofiber Cross-sectional Area

  • Myofiber Shortest Diameter

  • Myofiber Perimeter

  • Myofiber Location

  • Myofiber Circularity

  • Myofiber Fibertype

  • Number of Myofibers

  • Number of Central Nuclei per Myofiber


Reason #3: Faster Thresholding

An accurate threshold is the key to automated measurement. BIOQUANT has made significant progress in automating the creation of accurate thresholds.

Scroll Wheel threshold Adjustment

Fine-tune the Threshold By Scrolling the Mouse Wheel
Starting with the initial color, scrolling the mouse wheel up will search the image for similar colors and add them to the threshold automatically. Scrolling the mouse wheel down will find the colors in the threshold that are least similar to the initial color and remove them automatically.


Automatically Remove Threshold Associated with Non-specific Staining
The "Clean" button searches the image for all "small" bits of threshold and deletes them. This makes it quick to isolate the important parts of an image from the surrounding tissue despite non-specific background staining.

Keep Just What you Want
The "Keep" button allows you to mark just the parts of the threshold you need and then deletes the rest.

Precise Threshold Editing

Precise multi-band thresholding means you can combine multiple highly specific color ranges into one composite threshold. You can capture all the subtle variations in a stain. You can identify both lightly stained and darkly stained cells at the same time. You can identify cells stained with different fluorochromes at the same time.

Assign Contrasting Threshold Colors

Threshold colors can be assigned to specific arrays now. This means your threshold color will always contrast well with the both the specific stain you're trying to measure and the counterstain.

BIOQUANT Life Science uses a new palette of high-contrast colors.

BIOQUANT Life Science uses a new palette of high-contrast colors.


Reason #4: Faster Imaging

4GB Support for digital scans in TIF, BMP, & BIF Format

Open scans in the TIF, BMP, or BIF image formats. This makes it easy to work with digital slides from BIOQUANT SCAN and many other digital pathology scanners. With a 20X lens, that's more than 300 mm2 of tissue.

Crop within the Large Image Navigator

Having access to the entire section, means BIOQUANT can zoom out to rapidly measure large structures hippocampus area, then zoom in to measure cells within any structure. All this combines to make data collection fast.

Store camera Settings in Camera Presets

Camera presets make is simple to switch between brightfield, polarized light, and fluorescence imaging.

Presets store exposure time, gain, and white balance settings to standardize imaging and reduce setup times.

BIOQUANT SCAN - Add features to BIOQUANT Life Science

BIOQUANT SCAN controls a motorized stage with the help of an autofocus camera to automatically scan histology slides or well plate cultures. Analysis of digital scans is faster to perform and easier to train.

BIOQUANT can zoom out to measure referent data at one time for the entire section. Moving around a high magnification is faster and simpler when all you need to do is drag a box around the Large Image Navigator.


Reason #5: Faster Training with Guides and Videos

Learn from Integrated Video Tutorials

Play Button for Integrated Video Tutorials make it easy to find the help you need when you need it. For example, click the play button in the Measurement region to learn about the various measurement tools. Click the play button in the Threshold region to learn how to automatically identify stained cells.

Get Started quickly with Tutorial Guides


A Warm Welcome

When BIOUQANT starts, a welcome screen appears. This allows students to start one of the many tutorials, continue where they left off, or start a new project.

Start a Tutorial

BIOQUANT comes with an ever-expanding library of tutorials. Some tutorials focus on general system functionality. Others focus on collecting specific kinds of data from particular tissues.

Tutorials include standard data templates, instructional guides, and sample histology.


Reason #6: Faster Protocol Setup

Simplify procedures by Assigning Settings to Arrays

BIOQUANT now allows nearly every stage of a protocol to be assigned to measurement arrays reducing most protocols to only a handful of steps. You can assign threshold color, measurement color, preview color, calibration, topo array, region of interest type, threshold type, threshold range, measurement type, outline filter settings, measurement filter settings.

JUMPSTART ProtocolS by Assigning Files to Data sets

Files used with the data sets like Guides, Selected Lists, Calculation Lists, Measurement Filters, and Threshold Ranges can be assigned to dataset. Default assignments have already been made to every template dataset in BIOQUANT.


Reason #7: Faster Data Collection

Updated data set templates Reduce Steps

Our constant goal at BIOQUANT is to improve the speed of data collection. Standard analysis templates are continuously improved. Many steps have been eliminated, making data collection faster.


Reason #8: Faster Specialized Tools

Automated Cell counting

One of the primary tasks of BIOQUANT is the automated analysis of cell populations. A specialized tool set makes this work fast and simple even for students who are new to image analysis. Here's an example of how the protocol works for the analysis of axon number, cross-sectional area, and diameter.

Automated analysis of Skeletal Myofibers

Analysis of skeletal muscle in particularly challenging because so many different parameters must be measured for each muscle cell. Most often these are: myofiber cross-sectional area, roundness, shortest diameter, position, optical density (for fibertyping), and number of central nuclei. BIOQUANT now includes a specialized tool precisely for this task.

rapid analysis of mri data


The new DICOM navigator for MRI data, quickly analyze the volume and shape of structures.

Compatible with batch processing, BIOQUANT can rapidly analyze stacks of DICOM format images.

To aid in visualizing data, a set of 8 new pseudocolor palettes make monochromatic data more vibrant.


Reason #9: Faster Help with Technical Service Plans



Labs with active Technical Service Plans receive on-demand training via remote desktop sharing. Use this service to train new students, learn new software features, and design new data collection protocols.

Custom Analysis Template Design

Work with our technicians to develop customized analysis templates. Start with one of our standard templates and improve it to match your samples. Or, build your own unique protocols from the ground up.

Priority technical support

Get quick solutions to software and hardware problems by phone, email, or remote desktop.

Continuous Software upgrades

Each year, BIOQUANT publishes an upgrade to BIOQUANT Life Science that is included at no charge as part of the Technical Services Plan. New versions add features requested by the community, consolidate protocol steps, and introduce new types of measurement tools.


Reason #10: Simply Faster

This version of BIOQUANT LIFE SCIENCE takes the longest strides toward distilling the complexity of analyzing biological tissues down to the simplest of procedures.

With a standardized workflow documented with both written and video tutorials, BIOQUANT combines intelligent object detection with simple tools for manual correction to rapidly analyze even the most complex biological samples. Let us help your lab today.